PI Name & Affiliation:

Dr. Everette Jacob Remington Nelson,
Associate Professor,
School of Bio Sciences and Technology (SBST),
Vellore Institute of Technology, India

Co-PI Name & Affiliations:

Dr. Priyanka Srivastava,
Assistant Professor (Sr.),
School of Bio Sciences and Technology (SBST),
Vellore Institute of Technology, India

Dr. Raunak Kumar Das,
Assistant Professor,
Centre for Biomaterials, Cellular and Molecular Theranostics,
Vellore Institute of Technology, India

Funding Agency: Defence Research & Development Organisation (DRDO)

Scheme: Soldier Health & Drug Development

Overlay: 38,12,000

Duration of the Project: 3 Years

Dr. Everette Nelson

Associate Professor

Dr. Priyanka Srivastava

Assistant Professor (Sr.)

Dr. Raunak Kumar Das

Assistant Professor


Project Description

The proposed work aims to address the life-threatening physical injuries suffered by our Indian soldiers on the warfront. The most common type of physical injury is inflicted by gunshot wounds, which are often associated with bleeding, broken bones, organ damage, infection of the wound, or loss of ability to move the body part. Long-term complications also include lead poisoning and post-traumatic stress disorder. Hence, quick response time to treatment provided to the soldiers is critical for both their physical and mental well-being. We aim to develop a method using alginate-capped silver nanoparticles and adipose-derived stem cells embedded on a collagen matrix (CAAgNP-ASC), to provide holistic healing that will not only protect the wounds from microbial infestation, but also regenerate the underlying adipose tissue that is often lost in severe burn cases. We believe that the proposed method would lead to a much quicker and complete healing of even the 3˚ wounds, as compared to the ones currently available in the market.